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Patients with growth hormone insufficiency had worse disability scores, greater depression, greater fatigue, and poorer emotional well-being, compared to brain injury patients with normal neurosteroid levels

457 The production of iron-dependent hydroxyl radicals has been associated with muscle necrosis in a mouse model of DMD, and iron deprivation can decrease muscle necrosis and has potential therapeutic benefits

PMID: 30651162

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It is studied as a putative cortical-neuron bioregulator, and a peptide-DNA gene-modulation mechanism has been proposed by the originating group [8] a hypothesis that is not independently validated